Refrigerated Centrifuges
Refrigerated centrifuges are equipped with built-in cooling systems that allow them to maintain low temperatures while processing samples. These centrifuges are designed to spin samples at high speeds while keeping the temperature within a controlled range, typically between 4°C and 25°C, depending on the specific model and application. The refrigeration feature is crucial for preserving the integrity of temperature-sensitive biological materials during centrifugation. A variety of rotors and adapters are available to accommodate a range of tube and container sizes.
Refrigerated centrifuges are commonly used for laboratory applications involving biological samples, such as DNA, RNA, proteins, cells, and other sensitive biomolecules. For example, in molecular biology, DNA and RNA extraction, protein purification, and cell culture processes often require refrigeration to prevent the degradation or denaturation of the sample. High temperatures can cause proteins to unfold or enzymes to lose activity, while nucleic acids can degrade without proper cooling. They are also essential when handling samples that might produce heat during centrifugation, such as blood or plasma. If these samples are not kept cool, there is a risk of coagulation, cell lysis, or other changes that could compromise the accuracy of subsequent tests. Additionally, refrigerated centrifuges are used in clinical labs for blood fractionation and in research for cell sorting, organelle isolation, or preparing samples for further biochemical analysis. Refrigerated centrifuges ensure that these biological components remain stable and functional throughout the separation process.